Vasculitis & polymyalgia rheumatica

A glossary of signs and symptoms of giant cell arteritis

Ann Rheum DisPublished Delphi consensus study

Authors' conclusion

A glossary of definitions for 23 signs and symptoms of GCA was developed through a consensus process involving international experts.

Study context

Population
International task force (32 members from 11 countries) defining signs and symptoms of giant cell arteritis (GCA), primarily for research settings
Participants
32 participants11 countries
Outcome
Consensus-based definitions of signs and symptoms of GCA
Methodological details2-round Delphi, international task force, 4 online meetings, Core definitions extracted from 11 RCTs of GCA from a prior systematic literature review, supplemented by other sources such as rheumatology textbooks
  • 2-round Delphi
  • International task force
  • 4 online meetings
  • Core definitions extracted from 11 RCTs of GCA from a prior systematic literature review, supplemented by other sources such as rheumatology textbooks

Recommendations

As reported in the abstract

Signs and symptoms of GCA reviewed

29

Previously defined in the literature

6

High level of agreement reached on definition

23

Considered characteristic of GCA (headache, temporal artery abnormalities, scalp tenderness, scalp necrosis, jaw claudication, tongue claudication, tongue necrosis, amaurosis fugax, permanent vision loss, fever, limb claudication, blood pressure inequality)

12

Original publication

A glossary of signs and symptoms of giant cell arteritis. Ann Rheum Dis. Published 28 July 2025. doi:10.1016/j.ard.2025.06.2126

Composed by AI from the published abstract and checked against it. How Briefs are made →

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