Vasculitis & polymyalgia rheumatica
A glossary of signs and symptoms of giant cell arteritis
Authors' conclusion
A glossary of definitions for 23 signs and symptoms of GCA was developed through a consensus process involving international experts.
Study context
- Population
- International task force (32 members from 11 countries) defining signs and symptoms of giant cell arteritis (GCA), primarily for research settings
- Participants
- 32 participants11 countries
- Outcome
- Consensus-based definitions of signs and symptoms of GCA
Methodological details2-round Delphi, international task force, 4 online meetings, Core definitions extracted from 11 RCTs of GCA from a prior systematic literature review, supplemented by other sources such as rheumatology textbooks
- 2-round Delphi
- International task force
- 4 online meetings
- Core definitions extracted from 11 RCTs of GCA from a prior systematic literature review, supplemented by other sources such as rheumatology textbooks
Recommendations
As reported in the abstract
Signs and symptoms of GCA reviewed
29
Previously defined in the literature
6
High level of agreement reached on definition
23
Considered characteristic of GCA (headache, temporal artery abnormalities, scalp tenderness, scalp necrosis, jaw claudication, tongue claudication, tongue necrosis, amaurosis fugax, permanent vision loss, fever, limb claudication, blood pressure inequality)
12
Original publication
A glossary of signs and symptoms of giant cell arteritis. Ann Rheum Dis. Published 28 July 2025. doi:10. 1016/ j. ard. 2025. 06. 2126
Composed by AI from the published abstract and checked against it. How Briefs are made →