2024 American College of Rheumatology ( ACR ) Guideline for the Screening, Treatment, and Management of Lupus Nephritis

Sammaritano, LR; Askanase, A; Bermas, BL; Dall'Era, M; Duarte-García, A; Hiraki, LT; Rovin, BH; Son, MBF; Alvarado, A; Aranow, C; Barnado, A; Broder, A; Brunner, HI; Chowdhary, V; Contreras, G; Felix, C; Ferucci, ED; Gibson, KL; Hersh, AO; Izmirly, PM; Kalunian, K; Kamen, D; Rollins, B; Smith, BJ; Thomas, A; Timlin, H; Wallace, DJ; Ward, M; Azzam, M; Bartels, CM; Cunha, JS; DeQuattro, K; Fava, A; Figueroa-Parra, G; Garg, S; Greco, J; Cuéllar-Gutiérrez, MC; Iyer, P; Johannemann, AS; Jorge, A; Kasturi, S; Kawtharany, H; Khawandi, J; Kirou, KA; Legge, A; Liang, KV; Lockwood, MM; Sanchez-Rodriguez, A; Turgunbaev, M; Williams, JN; Turner, AS; Mustafa, RA

doi:10.1002/acr.25528

Lupus & antiphospholipid syndrome

2024 American College of Rheumatology ( ACR ) Guideline for the Screening, Treatment, and Management of Lupus Nephritis

Arthritis Care Res (Hoboken)Published 7 May 2025Clinical practice guideline

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Cite

Methodological detailsGRADE methodology, systematic literature reviews, PICO format, Voting Panel consensus ≥70%

GRADE methodology
Systematic literature reviews
PICO format
Voting Panel consensus ≥70%

Recommendations

As issued by the authors

LN therapy is continuous and ongoing, rather than consisting of discrete induction/initial and maintenance/subsequent therapies
Therapy should include pulse GC followed by oral GC taper and two additional immunosuppressive agents for 3-5 years for those achieving complete renal response

Reference

Issued by: ACR
Document: Guideline
Scope: Screening, treatment and management of LN; 28 graded recommendations (7 strong, 21 conditional) and 13 ungraded, consensus-based good practice statements

Authors: Sammaritano LR, Askanase A, Bermas BL, Dall'Era M, Duarte-García A, Hiraki LT, et al.
All 52 authors
Sammaritano LR, Askanase A, Bermas BL, Dall'Era M, Duarte-García A, Hiraki LT, Rovin BH, Son MBF, Alvarado A, Aranow C, Barnado A, Broder A, Brunner HI, Chowdhary V, Contreras G, Felix C, Ferucci ED, Gibson KL, Hersh AO, Izmirly PM, Kalunian K, Kamen D, Rollins B, Smith BJ, Thomas A, Timlin H, Wallace DJ, Ward M, Azzam M, Bartels CM, Cunha JS, DeQuattro K, Fava A, Figueroa-Parra G, Garg S, Greco J, Cuéllar-Gutiérrez MC, Iyer P, Johannemann AS, Jorge A, Kasturi S, Kawtharany H, Khawandi J, Kirou KA, Legge A, Liang KV, Lockwood MM, Sanchez-Rodriguez A, Turgunbaev M, Williams JN, Turner AS, Mustafa RA
Journal: Arthritis Care & Research
Published: 7 May 2025
DOI: 10.1002/acr.25528
PubMed: 40127995

Topic: Lupus & antiphospholipid syndrome

Original publication

2024 American College of Rheumatology ( ACR ) Guideline for the Screening, Treatment, and Management of Lupus Nephritis. Arthritis Care Res (Hoboken). Published 7 May 2025. doi:10.1002/acr.25528

Read the original article ↗

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