Validation and characterization of venous thromboembolism diagnoses in the Swedish National Patient Register among patients with rheumatoid arthritis
Authors' conclusion
This study demonstrates high validity for VTE diagnoses recorded in the NPR for patients with RA, thus confirming that the NPR may be used to identify prevalent VTE as well as incident VTE events in patients with RA.
Study context
- Population
- Patients with rheumatoid arthritis (RA) with VTE events (ICD-10 codes) registered in the Swedish National Patient Register (NPR) at hospitals in Region Stockholm, 2009–2018
- Participants
- 269 VTE events
- Outcome
- PPV of registered VTE diagnoses
Methodological detailsmanual chart review, random sample
- Manual chart review
- Random sample
Performance
As reported in the abstract
PPV of VTE diagnosis
PPV, overall VTE diagnosis
95%
PPV, incident VTE events
87%
PPV range across six alternative definitions of incident VTE
80% to 98%
Further findings
Confirmed incident VTE events diagnosed in relation to RA
- Confirmed incident VTE events
- 235
- Cases from work-up for presumed RA-related sign or symptom
- 3
- Cases where work-up involved a rheumatologist
- 17
- Vast majority diagnosed independently of RA
Original publication
Validation and characterization of venous thromboembolism diagnoses in the Swedish National Patient Register among patients with rheumatoid arthritis. Scand J Rheumatol. Published 13 January 2022. doi:10.
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