Fibromyalgia & musculoskeletal pain
Vagal nerve stimulation and fibromyalgia: an additional therapeutic option
Authors' conclusion
In conclusion, our preliminary results show that the treatment with AVNT™ reduced disease severity and improved sleep quality in FM patients.
Study context
- Population
- Patients with fibromyalgia (FM)
- Participants
- 18 patients
- Outcome
- Disease severity and sleep quality
- Follow-up
- Week 4
Methodological detailssingle-group
- Single-group
Main finding
As reported in the abstract
- Reduction in WPI score at week 2
- p=0.03
- Reduction in WPI score at week 4
- p=0.004
- Reduction in revised Fibromyalgia Impact Questionnaire (rFIQ) total score
- p=0.02
- Reduction in rFIQ general health component
- p=0.002
- Reduction in rFIQ symptoms component
- p<0.001
- Reduction in Pittsburgh Sleep Quality Index (PSQI) level
- p=0.02
Further findings
Serum Brain Derived Neurotrophic Factor (BDNF) levels · 2 and 4 weeks
- No significant changes in BDNF levels after two or four weeks
Original publication
Vagal nerve stimulation and fibromyalgia: an additional therapeutic option. Clin Exp Rheumatol. Published 27 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →