Unexpectedly high incidence of Kawasaki Disease in a Canadian Atlantic Province- an 11-year retrospective descriptive study
Authors' conclusion
We have confirmed an incidence of KD in our population which is higher than that reported in Europe and other regions of North America despite our small Asian population.
Study context
- Population
- Children <16 years old from Nova Scotia diagnosed with Kawasaki Disease (KD) between 2007–2018
- Participants
- 220 children
- Outcome
- Annual incidence of KD
Methodological detailspopulation-based, 2007-2018, cases identified using administrative and clinical databases, health record review
- Population-based
- 2007-2018
- Cases identified using administrative and clinical databases
- Health record review
Main finding
As reported in the abstract
Annual incidence of KD per 100,000 children <5 years
Annual incidence per 100,000 children <5 years
29.6
Observational data: associations, not effects.
Further findings
Disease criteria and demographics
- Complete KD
- 61.4%
- Incomplete KD
- 23.2%
- Male to female ratio
- 1.3:1
- Median age, years
- 3.6
Refractory to first intravenous immunoglobulin (IVIG) dose
- Refractory to first dose
- 23 (12%)
- All patients diagnosed in the acute phase received IVIG
Safety
- Coronary artery aneurysms
- 13 (6%)
- Death with multiple giant aneurysms
- 1
Original publication
Unexpectedly high incidence of Kawasaki Disease in a Canadian Atlantic Province- an 11-year retrospective descriptive study. Pediatr Rheumatol Online J. Published 3 April 2023. doi:10. 1186/ s12969-023-00805-y
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