Pediatric rheumatology

Unexpectedly high incidence of Kawasaki Disease in a Canadian Atlantic Province- an 11-year retrospective descriptive study

Pediatr Rheumatol Online JPublished Retrospective descriptive study

Authors' conclusion

We have confirmed an incidence of KD in our population which is higher than that reported in Europe and other regions of North America despite our small Asian population.

Study context

Population
Children <16 years old from Nova Scotia diagnosed with Kawasaki Disease (KD) between 2007–2018
Participants
220 children
Outcome
Annual incidence of KD
Methodological detailspopulation-based, 2007-2018, cases identified using administrative and clinical databases, health record review
  • Population-based
  • 2007-2018
  • Cases identified using administrative and clinical databases
  • Health record review

Main finding

As reported in the abstract

Annual incidence of KD per 100,000 children <5 years

Annual incidence per 100,000 children <5 years

29.6

Observational data: associations, not effects.

Further findings

Disease criteria and demographics

Complete KD
61.4%
Incomplete KD
23.2%
Male to female ratio
1.3:1
Median age, years
3.6

Refractory to first intravenous immunoglobulin (IVIG) dose

Refractory to first dose
23 (12%)
  • All patients diagnosed in the acute phase received IVIG

Safety

Coronary artery aneurysms
13 (6%)
Death with multiple giant aneurysms
1

Original publication

Unexpectedly high incidence of Kawasaki Disease in a Canadian Atlantic Province- an 11-year retrospective descriptive study. Pediatr Rheumatol Online J. Published 3 April 2023. doi:10.1186/s12969-023-00805-y

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