Rheumatoid arthritis

Unacceptable Work State in Rheumatoid Arthritis: Establishment of Thresholds for Presenteeism and Clinical Measurement Instruments

J RheumatolPublished Threshold-derivation study within a multinational prospective cohort

Authors' conclusion

The final thresholds to assess unacceptable presenteeism for axSpA were also chosen as most accurate for use in RA. In addition, accurate thresholds of pain reflecting unacceptable work state are available.

Study context

Population
Employed patients with rheumatoid arthritis (RA) in the multinational RA-PROSE study
Participants
104 employed patients
Outcome
Thresholds of presenteeism instruments and pain reflecting unacceptable work state
Follow-up
Baseline
Methodological detailsRA-PROSE, ROC-based threshold derivation, 12-month follow-up
  • RA-PROSE
  • ROC-based threshold derivation
  • 12-month follow-up

Performance

As reported in the abstract

Optimal thresholds for unacceptable work state
Unacceptable work state (patient-considered)
15%
Thresholds developed in RA: good performance vs external criterion
AUC > 0.75
Quantity and Quality (QQ) method threshold performance
AUC 0.62
WPAI-presenteeism
≥ 40
QQ method
< 97
Workplace Activity Limitations Scale
≥ 0.75
25-item Work Limitations Questionnaire with modified physical demands scale
≥ 29
Pain intensity
≥ 4

Further findings

Prediction of adverse work outcomes (AWO) · 12 months

Unacceptable work state patients with ≥1 AWO
7 (7%)
Pain and WPAI performed best in predicting AWO

Original publication

Unacceptable Work State in Rheumatoid Arthritis: Establishment of Thresholds for Presenteeism and Clinical Measurement Instruments. J Rheumatol. Published 1 February 2025. doi:10.3899/jrheum.2024-0833

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