Vasculitis & polymyalgia rheumatica

Turkish Society for Rheumatology recommendations for the diagnosis, follow-up and management of giant cell arteritis

Clin Exp RheumatolPublished Guideline

Methodological detailsrecommendations, systematic literature review (PRISMA), PICO format, Oxford system for grading evidence and strength of recommendation
  • Recommendations
  • Systematic literature review (PRISMA)
  • PICO format
  • Oxford system for grading evidence and strength of recommendation

Recommendations

As issued by the authors

  1. MTX in addition to GC as first-line treatment in all patients with giant cell arteritis (GCA) without ischaemic symptoms

  2. LEF, AZA and MMF as alternatives in these patients if MTX is not tolerated

  3. Tocilizumab in GCA patients with ischaemic symptoms or with refractoriness to at least one conventional immunosuppressive

  4. Upadacitinib as an alternative to tocilizumab in patients with low cardiovascular risk

Original publication

Turkish Society for Rheumatology recommendations for the diagnosis, follow-up and management of giant cell arteritis. Clin Exp Rheumatol. Published 21 December 2025. doi:10.55563/clinexprheumatol/sghxo3

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