Vasculitis & polymyalgia rheumatica
Trends in mortality due to granulomatosis with polyangiitis (GPA)/microscopic polyangiitis (MPA) across Europe: insights from a decade of death registrations
Authors' conclusion
Despite major advances in disease management, our results show that deaths due to GPA and MPA were stable over the last decade
Study context
- Population
- Deaths recorded with GPA or MPA as underlying cause of death, 29 European countries, 2011–202129 European countries
- Outcome
- Trends in mortality due to GPA and MPA (crude mortality rates and standardised mortality rates (SMRs))
- Follow-up
- 2011-2021
Methodological detailsEurostat publicly available data, linear regression of mortality rates over time, stratified by age and sex, choropleth map; SMR plotted against latitude
- Eurostat publicly available data
- Linear regression of mortality rates over time
- Stratified by age and sex
- Choropleth map; SMR plotted against latitude
Main finding
As reported in the abstract
Mortality due to GPA and MPA over time
Rising age at death: median age-band at start
70-74
Rising age at death: median age-band at end
75-79
Observational data: associations, not effects.
Further findings
Between-country differences in SMR
- Highest SMR, Denmark (per 10 million)
- 31.03
- Lowest SMR, Romania (per 10 million)
- 0.77
Mortality by age and sex
- Mortality rates higher in adults aged over 80 years
- More deaths in men than women
Latitudinal gradient in SMR
- Latitudinal gradient seen in GPA but not MPA; highest mortality rates in Scandinavia
Original publication
Trends in mortality due to GPA/MPA across Europe: insights from a decade of death registrations. Rheumatology (Oxford). Published 20 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →