Vasculitis & polymyalgia rheumatica
Dental infection is associated with early relapse in patients with ANCA-associated vasculitis
Main finding · Composite of relapse or all-cause mortalityResult — go to the resultAdjusted hazard ratio 3.78 95% CI 1.13–12.66Authors' conclusion
Severe dental infections were associated with increased risk of early relapse or mortality in AAV.
Study context
- Population
- Patients newly diagnosed with antibody-associated vasculitis (AAV) between January 2011 and July 2022 (median age 74 years)
- Participants
- 93 patients
- Exposure
- Severe dental infection vs no severe dental infection
- Dental infectionn = 41
- Outcome
- Vasculitis relapse or all-cause mortality
- Follow-up
- Within 1 year of treatment initiation
Methodological detailsCox proportional hazards models
- Cox proportional hazards models
Main finding
Composite of:
· 1 year
Adjusted hazard ratio
3.78
95% CI 1.13–12.66
P = 0.031
Dental infectionvs Control
aHR 3.78 (95% CI 1.13–12.66); P = 0.031
As reported in the abstract
Observational data: associations, not effects.
Further findings
Composite events in whole cohort · 1-year follow-up
- Relapses
- 13
- Deaths
- 2
- Composite event rate per 100 person-years
- 20.9
Composite outcome by tooth extraction among patients with dental infections (exploratory)
- Composite outcome rates similar regardless of tooth extraction
- Exploratory analysis
Original publication
Dental infection is associated with early relapse in patients with ANCA-associated vasculitis. RMD Open. Published 17 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →