Spondyloarthritis & psoriatic arthritis

Treatment decisions in axial spondyloarthritis daily clinical practice are more than treat-to-target

Rheumatology (Oxford)Published Cross-sectional study

An erratum to this article was published (Rheumatology (Oxford), 4 Jan 2024 ↗)

Authors' conclusion

This study shows that physicians do not always strictly apply treat-to-target in case of residual disease activity in axSpA. Usually, they accept low disease activity as satisfactory.

Study context

Population
Patients with a clinical diagnosis of axial spondyloarthritis (axSpA) ≥6 months
Participants
249 patients
Outcome
Residual disease activity according to physician's opinion, patient's opinion and composite indices compared with subsequent treatment decisions
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Remission according to the physician
115/249 (46%)
Of those in physician-rated remission, remission according to BASDAI
37% (n = 43)
Treatment left unchanged in patients with residual disease activity per physician and BASDAI >3.5
51/83 (60%)
Unchanged because of low disease activity as rated by physician
n = 15 (29%)
Unchanged because of low disease activity with non-inflammatory complaints or comorbidities
n = 11 (25%)

Observational data: associations, not effects.

Original publication

Treatment decisions in axial spondyloarthritis daily clinical practice are more than treat-to-target. Rheumatology (Oxford). Published 6 April 2023. doi:10.1093/rheumatology/kead155

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