Spondyloarthritis & psoriatic arthritis
New bone formation at the sacroiliac joint in axial spondyloarthritis: characterization of backfill in MRI and CT
Authors' conclusion
All joint space lesions show increased density and might contain calcified matrix, suggesting new bone formation, with a gradual increase in the proportion of calcified matrix towards type C lesions (backfill).
Study context
- Population
- Patients with axSpA who underwent both CT and MRI of the SI joints in two prospective studies97 patients with axSpA
- Comparison
- MRI joint space lesion types A, B and C vs cartilage, spongious bone and cortical bone on CT (Hounsfield units (HU))
- Type An = 48
- Type Bn = 88
- Type Cn = 84
- Outcome
- CT density (HU) of MRI SI joint space lesions and surrounding cartilage and bone
Methodological detailsimage fusion, three readers
- Image fusion
- Three readers
Main finding
As reported in the abstract
P = 0.93
- Lesion HU values significantly higher than cartilage and spongious bone, but lower than cortical bone
- P < 0.001
- Type C lesions denser than type A and B lesions
- P < 0.001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
New bone formation at the sacroiliac joint in axial spondyloarthritis: characterization of backfill in MRI and CT. Rheumatology (Oxford). Published 5 April 2023. doi:10. 1093/ rheumatology/ kead142
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