Total Hip Replacement or Resistance Training for Severe Hip Osteoarthritis
Primary result · Oxford Hip Score, mean increase (improvement)Result — go to the resultDifference 11.4 points 95% CI 8.9–14.0Authors' conclusion
In patients 50 years of age or older who had severe hip osteoarthritis and an indication for surgery, total hip replacement resulted in a clinically important, superior reduction in hip pain and improved hip function, as reported by patients, at 6 months as compared with resistance training.
Study context
- Population
- Patients aged ≥50 years with severe hip OA and an indication for surgerymean age 67.6 years
- Participants
- 109 patients
- Comparison
- Total hip replacement vs resistance training
- Total hip replacementn = 53
- Resistance trainingn = 56reference
- Primary endpoint
- Change in patient-reported hip pain and function, Oxford Hip Score (0–48, higher scores indicating less pain and better function)
- Follow-up
- 6 months
Methodological detailsmulticentre
- Multicentre
Primary result
Oxford Hip Score, mean increase (improvement)
Difference
11.4 points
95% CI 8.9–14.0
P < 0.001
Change by group
Total hip replacement
15.9
mean · points
Resistance training
4.5
mean · points
Total hip replacementvs Resistance training
difference 11.4 points (95% CI 8.9–14.0); P < 0.001
As reported in the abstract
Further findings
Crossover/non-adherence to assigned treatment · 6 months
- Crossover/non-adherence to assigned treatment: Total hip replacement: had not undergone surgery; Resistance training: had undergone total hip replacement
Safety
Serious adverse events · 6 months
- Incidence similar in the two groups; majority were known complications of total hip replacement
Original publication
Total Hip Replacement or Resistance Training for Severe Hip Osteoarthritis. N Engl J Med. Published 31 October 2024. doi:10. 1056/ nejmoa2400141
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