Time Trends and Predictors of Gout Remission Over 6 Years
Authors' conclusion
On ULT, fulfillment of remission increases over time and remission can be achieved in most patients.
Study context
- Population
- People with gout and CVD taking urate-lowering therapy (ULT), with at least 1 year of follow-up data
- Comparison
- Febuxostat vs allopurinol
- Primary endpoint
- Gout remission (simplified definition: no flares in past year, at least two serum urate <0.36 mmol/L in past year, no tophus)
- Follow-up
- 6 years
Methodological detailslogistic regression
- Logistic regression
Primary result
As reported in the abstract
Gout remission over time
Remission at year 1
37.4%
1,593/4,259
Remission at year 6
63.1%
322/510
Remission at least once over 6 years
59.4%
Further findings
Remission by treatment, first 2 years
- More participants receiving febuxostat achieved remission, primarily because of more achieving the serum urate remission domain
Baseline predictors of remission (multivariable analysis)
- Age, race, greater disease severity, comorbidities and febuxostat treatment significantly associated with remission
Original publication
Time Trends and Predictors of Gout Remission Over 6 Years. Arthritis Care Res (Hoboken). Published 28 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →