Systemic sclerosis & Raynaud's
Therapy satisfaction and health literacy are key factors to improve medication adherence in systemic sclerosis
Authors' conclusion
Although most SSc patients display good MA, non-adherence remains a major problem.
Study context
- Population
- Patients with Systemic Sclerosis (SSc) at the University of Lübeck, Germany
- Participants
- 85 patients
- Outcome
- Medication adherence (MA) measured by the Compliance Questionnaire of Rheumatology
Methodological detailsmonocentric
- Monocentric
Main finding
As reported in the abstract
Good MA (Compliance Questionnaire of Rheumatology)
- Good medication adherence (MA)
- 51.8%
- MA positively associated with therapy satisfaction
- p < 0.001
- MA positively associated with modified Rodnan Skin Score
- p = 0.032
- MA positively associated with age
- p = 0.025
- MA positively associated with intake of micronutrients
- p = 0.033
- MA positively associated with number of prescribed drugs
- p = 0.014
- MA negatively associated with weight loss attributed to SSc
- p = 0.009
- MA negatively associated with perception that disease is caused by patient's personality
- p = 0.011
- MA negatively associated with perception that disease is caused by patient's emotional state
- p = 0.037
Observational data: associations, not effects.
Further findings
Factors associated with MA
- Positive association: therapy satisfaction
- P < 0.001
- Positive association: mRSS
- P = 0.032
- Positive association: age
- P = 0.025
- Positive association: intake of micronutrients
- P = 0.033
- Positive association: number of prescribed drugs
- P = 0.014
- Negative association: weight loss attributed to SSc
- P = 0.009
- Negative association: perception that disease is caused by patient's personality
- P = 0.011
- Negative association: perception that disease is caused by emotional state
- P = 0.037
- Positive association: some dimensions of health literacy
Original publication
Therapy satisfaction and health literacy are key factors to improve medication adherence in systemic sclerosis. Scand J Rheumatol. Published 20 September 2022. doi:10.
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