The value of ultrasound-defined tenosynovitis and synovitis in the prediction of persistent arthritis
An erratum to this article was published (Rheumatology (Oxford), 1 Mar 2023 ↗)
Main finding · US-detected digit flexor tenosynovitis as predictor of persistence (independent of US joint synovitis and RF)Result — go to the resultOdds ratio 6.6 95% CI 2.0–22.1Authors' conclusion
US-defined tenosynovitis provided independent predictive data for the development of persistent arthritis.
Study context
- Population
- DMARD-naïve patients with clinically apparent synovitis of one or more joints and symptom duration ≤3 months (early arthritis)
- Participants
- 150 patients
- Exposure
- US-defined tenosynovitis vs US-defined synovitis and clinical and serological variables as predictors of persistent arthritis
- Persistent arthritisn = 99
- Resolving diseasen = 51reference
- Outcome
- Persistent vs resolving arthritis
- Follow-up
- 18 months
Methodological detailsmultivariate logistic regression
- Multivariate logistic regression
Main finding
As reported in the abstract
US-detected digit flexor tenosynovitis as predictor of persistence (independent of US joint synovitis and RF)
Odds ratio
6.6
95% CI 2.0–22.1
P = 0.002
Events by group
US-defined tenosynovitisvs US-defined synovitis and clinical and serological variables as predictors of persistent arthritis
OR 6.6 (95% CI 2.0–22.1); P = 0.002
Observational data: associations, not effects.
Further findings
US-defined digit flexor tenosynovitis as predictor in RF/ACPA-negative subcohort (adjusted for US joint synovitis)
| OR (95% CI) | P value | ||
|---|---|---|---|
| US-defined digit flexor tenosynovitis | 4.7 (1.4–15.8) | P = 0.012 | |
| 0.050.21520Odds ratio (log scale) |
Original publication
The value of ultrasound-defined tenosynovitis and synovitis in the prediction of persistent arthritis. Rheumatology (Oxford). Published 12 April 2022. doi:10.
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