Vasculitis & polymyalgia rheumatica

The value of axillary, facial, occipital, subclavian and common carotid arteries ultrasound in the diagnosis of giant cell arteritis

Rheumatology (Oxford)Published Retrospective cohort study

Authors' conclusion

Adding the evaluation of AXs to the TA ultrasound increased the number of patients diagnosed with GCA, even in cases of predominantly cranial symptoms.

Study context

Population
Patients with new-onset GCA and a positive US of the temporal artery (TA), AX, facial (FA), occipital (OC), subclavian (SC) or common carotid (CC), rheumatology departments of two academic centres
Exposure
TA US alone vs TA plus AX, FA, OC, SC or CC US
Outcome
Diagnostic value for GCA of adding AX to TA US
Methodological detailstwo academic centres
  • Two academic centres

Main finding

As reported in the abstract

Increase in diagnostic yield for GCA when added to TA US

Adding AX to TA US

9.6%

Adding OC to TA and AX US

1.4%

Adding SC to TA and AX US

1.8%

Observational data: associations, not effects.

Further findings

OutcomeValues
Positive US (halo sign) by arteryTA 89.6% · FA 48.8% · OC 24.6% · AX 24.3% · SC 54.4% · CC 20.6%

Negative TA US

Negative TA US
24/230 (10.4%)
AX involvement among negative TA US
22
Exclusive OC involvement
1
Exclusive SC involvement
1

Negative TA US but positive AX US by symptoms (subgroup)

With cranial symptoms
13
With exclusively cranial symptoms
4

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The value of axillary, facial, occipital, subclavian and common carotid arteries ultrasound in the diagnosis of giant cell arteritis. Rheumatology (Oxford). Published 8 June 2024. doi:10.1093/rheumatology/keae321

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