Vasculitis & polymyalgia rheumatica

Diagnostic yield of facial artery ultrasound in addition to temporal and axillary artery ultrasound for the diagnosis of giant cell arteritis

Clin Exp RheumatolPublished Retrospective diagnostic accuracy study

Authors' conclusion

FacUS provides limited additional diagnostic yield when added to temporal and axillary artery imaging in suspected GCA but may be performed in selected patients with strong clinical suspicion and negative temporal ultrasound findings.

Study context

Population
Patients with suspected giant cell arteritis (GCA) who underwent standardised tempUS and axUS with both facial arteries also examined37 GCA, 32 other conditions
Participants
69 patients
Comparison
FacUS added to tempUS and axUS vs tempUS and axUS
Outcome
Diagnostic accuracy (sensitivity, specificity) of facUS added to tempUS and axUS for GCA
Methodological detailsROC-curve analysis
  • ROC-curve analysis

Performance

As reported in the abstract

Diagnostic accuracy for GCA, facUS cutoff >0.7 mm
Test or modelSensitivitySpecificity
tempUS + axUS + facUS97.3% (+8.1%)65.6% (−18.8%)

tempUS + axUS + facUS

Sensitivity97.3% (+8.1%)
Specificity65.6% (−18.8%)

Further findings

FacUS-values >0.7 mm

Patients with facUS >0.7 mm (26 GCA, 8 non-GCA)
34
Patients with facUS >1.0 mm (17 GCA, 1 non-GCA)
18

Negative tempUS but positive facUS

Patients with negative tempUS but positive facUS
11
Of these, ultimately diagnosed with GCA
5
Of these, isolated facial artery involvement
3

Original publication

Diagnostic yield of facial artery ultrasound in addition to temporal and axillary artery ultrasound for the diagnosis of giant cell arteritis. Clin Exp Rheumatol. Published 13 April 2026. doi:10.55563/clinexprheumatol/pvnzvf

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