Systemic sclerosis & Raynaud's
The prevalence and incidence of Raynaud’s in England, United Kingdom
Authors' conclusion
Excluding people with Raynaud's secondary to an autoimmune connective tissue disease, this study observed an increasing number of incident cases of GP-recorded Raynaud's diagnoses with age, peaking at 40-69 years.
Study context
- Population
- Individuals with Raynaud's in England, CPRD Aurum, 1998 to 2023158,449 prevalent cases in 2023
- Outcome
- Prevalence (2023) and incidence (2003 to 2023) of Raynaud's, and association with age, sex, ethnicity and region
Methodological detailsClinical Practice Research Datalink Aurum database, logistic regression, Poisson regression, survival-time analyses
- Clinical Practice Research Datalink Aurum database
- Logistic regression
- Poisson regression
- Survival-time analyses
Main finding
As reported in the abstract
Prevalence rate per 100 000 people
894.19
95% CI 889.81, 898.58
Raynaud's cases recorded in 2023
158 449
Incidence rate per 100 000 person-years
46.22
95% CI 45.98, 46.47
Incident cases recorded
136 602
Observational data: associations, not effects.
Further findings
Prevalence by ethnicity and region · 2023
| OR (95% CI) | ||
|---|---|---|
| Black ethnicity | 0.54 (0.50–0.58) | |
| London | 0.50 (0.50–0.51) | |
| 0.512Odds ratio (log scale) |
Incidence by age, sex, ethnicity and region
| IRR (95% CI) | ||
|---|---|---|
| Older age | 1.04 (1.03–1.06) | |
| Females | 2.00 (1.98–2.01) | |
| Black ethnicity | 0.49 (0.46–0.52) | |
| London | 0.53 (0.52–0.54) | |
| 0.512Incidence rate ratio (log scale) |
Prevalence by ethnicity and region · 2023
- Older individuals and females most likely to develop Raynaud's
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →