Systemic sclerosis & Raynaud's

The prevalence and incidence of Raynaud’s in England, United Kingdom

Rheumatology (Oxford)Published Population-based cohort study

Authors' conclusion

Excluding people with Raynaud's secondary to an autoimmune connective tissue disease, this study observed an increasing number of incident cases of GP-recorded Raynaud's diagnoses with age, peaking at 40-69 years.

Study context

Population
Individuals with Raynaud's in England, CPRD Aurum, 1998 to 2023158,449 prevalent cases in 2023
Outcome
Prevalence (2023) and incidence (2003 to 2023) of Raynaud's, and association with age, sex, ethnicity and region
Methodological detailsClinical Practice Research Datalink Aurum database, logistic regression, Poisson regression, survival-time analyses
  • Clinical Practice Research Datalink Aurum database
  • Logistic regression
  • Poisson regression
  • Survival-time analyses

Main finding

As reported in the abstract

Prevalence of Raynaud's · 2023

Prevalence rate per 100 000 people

894.19

95% CI 889.81, 898.58

Raynaud's cases recorded in 2023

158 449

Incidence rate per 100 000 person-years

46.22

95% CI 45.98, 46.47

Incident cases recorded

136 602

Observational data: associations, not effects.

Further findings

Prevalence by ethnicity and region · 2023

OR (95% CI)
Black ethnicity0.54 (0.50–0.58)
London0.50 (0.50–0.51)

Incidence by age, sex, ethnicity and region

IRR (95% CI)
Older age1.04 (1.03–1.06)
Females2.00 (1.98–2.01)
Black ethnicity0.49 (0.46–0.52)
London0.53 (0.52–0.54)

Prevalence by ethnicity and region · 2023

Older individuals and females most likely to develop Raynaud's

Original publication

The prevalence and incidence of Raynaud’s in England, United Kingdom. Rheumatology (Oxford). Published 8 July 2026. doi:10.1093/rheumatology/keag328

Composed by AI from the published abstract and checked against it. How Briefs are made →

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