The incremental risk of fragility fractures in aging men
Authors' conclusion
In men without a pre-existing history of osteoporosis, the risk of fragility fractures starts to increase after the age of 70.
Study context
- Population
- Men older than 49 years without prior fragility fracture, high osteoporosis-risk comorbidities, or osteoporosis diagnosis/treatment
- Exposure
- Data-driven age strata vs youngest stratum
- Outcome
- Fragility fractures by age stratum
Methodological detailsdatabase study (PearlDiver Patient Records Database), stratum-specific likelihood ratio analysis, multivariable logistic regression
- Database study (PearlDiver Patient Records Database)
- Stratum-specific likelihood ratio analysis
- Multivariable logistic regression
Main finding
As reported in the abstract
Risk of fragility fracture by age stratum vs 50-64
Each group vs 50-64Relative risk (95% CI)P value
70-72multivariable regression; risk incrementally increased starting at 70-72
1.31(1.21–1.46)
P < 0.00181+highest risk
5.35(5.10–5.62)
P < 0.001Observational data: associations, not effects.
Original publication
The incremental risk of fragility fractures in aging men. Osteoporos Int. Published 8 November 2023. doi:10.
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