Systemic sclerosis & Raynaud's
Systemic Sclerosis in Individuals With Exposure to World Trade Center Ground Zero Rescue and Recovery Efforts: A Case Series
Authors' conclusion
A high frequency of ILD and overlap features were observed among patients with SSc with WTC exposure.
Study context
- Population
- Patients with systemic sclerosis (SSc) or SSc spectrum conditions who reported exposure to the World Trade Center (WTC) site (New York)7 completed exposure assessment
- Participants
- 11 patients
- Outcome
- Features of patients with SSc with WTC exposure
Main finding
As reported in the abstract
- Female
- 8
- Age at diagnosis, median (range), years
- 46 (36-75)
- Time from exposure to first non-RP SSc symptom, median (range), years
- 8 (1-19)
- Time from exposure to diagnosis, median (range), years
- 11 (2-18)
- SSc onset > 5 years from WTC exposure
- 55%
- lcSSc
- 5
- dcSSc
- 3
- SSc features meeting criteria for MCTD
- 1
- UCTD with features of SSc
- 2
- Overlapping features with other connective tissue disease (CTDs)
- 4
- Interstitial lung disease (ILD)
- 10
- History of tobacco use
- 5 of 11
- Other hazardous exposures outside WTC (questionnaire completers)
- 7 of 7
- Personal protective equipment use (among those with other exposures)
- 2
Observational data: associations, not effects.
Original publication
Systemic Sclerosis in Individuals With Exposure to World Trade Center Ground Zero Rescue and Recovery Efforts: A Case Series. J Rheumatol. Published 15 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →