Lupus & antiphospholipid syndrome
Systemic Lupus Erythematosus and the Ratio of Omega-3 to Omega-6 Fatty Acids Consumption among Women in the Adventist Health Study-2
Authors' conclusion
We observed a significant positive association between the ratio of omega-3 to omega-6 fatty acids consumption and prevalence of SLE.
Study context
- Population
- Women in the Adventist Health Study-2 cohort
- Participants
- 42,398 women
- Exposure
- Systemic Lupus Erythematosus (SLE) vs non-cases; quartiles of omega-3 to omega-6 ratio
- Outcome
- Association of omega-3 and omega-6 fatty acids consumption, and their ratio, with self-reported doctor told SLE diagnosis
Methodological detailsunconditional logistic regression
- Unconditional logistic regression
Main finding
As reported in the abstract
- Positive significant trend (p trend = 0.005)
- SLE reported higher intakes of total omega-3, about the same omega-6, and higher omega-3 to omega-6 ratios vs non-cases
Observational data: associations, not effects.
Further findings
- Initiation of fish oil around time of SLE diagnosis (among those reporting fish oil intake)
- 87%
Baseline omega-3 and fish oil intake in incident SLE cases (6-year follow-up, 64 cases)
- No different than among non-cases
Factors associated with SLE
- SLE more likely in Black vs White women, ever vs never smokers, overweight vs normal/underweight, and age 50-59 vs 30-49 years
Original publication
Systemic Lupus Erythematosus and the Ratio of Omega-3 to Omega-6 Fatty Acids Consumption among Women in the Adventist Health Study-2. Lupus. Published 5 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →