Systematic evaluation of abdominal aortic calcification in patients with a recent clinical fracture visiting the Fracture Liaison Service
Authors' conclusion
In FLS patients, the prevalence of AAC and severe AAC was 27.6% and 15.7%. Index fracture location and BMD were not associated with AAC or severe AAC. Prevalent VFs were associated with AAC, but not with severe AAC in the subgroup of patients without CVD.
Study context
- Population
- Patients aged 50–90 years with a recent clinical fracture attending the FLS
- Participants
- 1,731 patients
- Outcome
- Prevalence and severity of AAC (AAC-24 score: none, moderate 1-4, severe ≥ 5) on lateral spine DXA imaging
Methodological detailscross-sectional cohort, multivariate logistic regression
- Cross-sectional cohort
- Multivariate logistic regression
Main finding
As reported in the abstract
AAC prevalence
Abdominal aortic calcification (AAC) present
478
27.6%
Moderate AAC (of those with AAC)
207
43.3%
Severe AAC (of those with AAC)
271
56.7%
Severe AAC prevalence
15.7%
Observational data: associations, not effects.
Further findings
Factors associated with AAC presence
- AAC associated with age, BMI, smoking, history of cardiovascular disease (CVD) and prevalent grade 2 or 3 VFs
- Index fracture location and bone mineral density (BMD) not associated with AAC or severe AAC
Patients with AAC without history of CVD (subgroup)
- Subgroup size
- 318
- No association between index fracture location and BMD
- Severe AAC not associated with prevalent VFs
Original publication
Systematic evaluation of abdominal aortic calcification in patients with a recent clinical fracture visiting the Fracture Liaison Service. Osteoporos Int. Published 12 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →