Autoinflammatory & rare systemic diseases
Still’s disease continuum from childhood to elderly: data from the international AIDA Network Still’s disease registry
Authors' conclusion
Despite some minor difference between groups, overall, demographic, clinical, laboratory and treatments aspects of Still's disease were similarly observed in patients at all ages.
Study context
- Population
- Patients with Still's disease in the International AutoInflammatory Disease Alliance (AIDA) Network registry
- Participants
- 411 patients
- Exposure
- Paediatric-onset vs adult-onset vs elderly-onset Still's disease
- Paediatric-onsetn = 65
- Adult-onsetn = 314
- Elderly-onsetn = 32
- Outcome
- Differences in demographic, clinical features and response to treatment between paediatric-onset, adult-onset and elderly-onset Still's disease
Methodological detailsinternational registry, multicentre
- International registry
- Multicentre
Main finding
As reported in the abstract
Paediatric-onset vs Adult-onset: P = 0.004 · Paediatric-onset vs Adult-onset: P = 0.009 · Paediatric-onset vs Adult-onset: P = 0.007 · Elderly-onset vs Paediatric-onset: P = 0.015 · Elderly-onset vs Paediatric-onset: P < 0.0001 · Paediatric-onset vs Adult-onset: P < 0.0001
Observational data: associations, not effects.
Original publication
Still’s disease continuum from childhood to elderly: data from the international AIDA Network Still’s disease registry. RMD Open. Published 1 December 2023. doi:10.
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