Spatiotemporal changes in imaging features associated with diffuse idiopathic skeletal hyperostosis (DISH)

RMD OpenPublished Retrospective cohort study

Authors' conclusion

This is the first characterisation of spatiotemporal features across all phases of DISH, indicating that progression of DISH is characterised by distinct features at different phases along the disease continuum.

Study context

Population
Individuals with repeated CT scans of the thoracic spine (83 female, 74 male), followed an average of 2.7 years (range 0.2 to 15.0)83 female and 74 male
Exposure
DISH vs Early-phase DISH vs Not meeting either criterion
Outcome
Completeness of ectopic bridging across the thoracic spine and corresponding disease status
Follow-up
Average of 2.7 years (range from 0.2 to 15.0 years)
Methodological detailsrepeated CT scans of the thoracic spine, Rochester Epidemiology Project
  • Repeated CT scans of the thoracic spine
  • Rochester Epidemiology Project

Main finding

As reported in the abstract

Spatiotemporal imaging changes along the DISH continuum

Individuals with imaging changes over time resulting in a revised diagnosis along the DISH continuum

Over 15%

Early-phase DISH: new involvement of previously unaffected motion segments, estimated time

2.1 years

Advanced DISH: increased prevalence of complete bridging (average two of three available motion segments), estimated time

2.6-2.9 years

Observational data: associations, not effects.

Original publication

Spatiotemporal changes in imaging features associated with diffuse idiopathic skeletal hyperostosis (DISH). RMD Open. Published 27 April 2024. doi:10.1136/rmdopen-2024-004074

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