Spatiotemporal changes in imaging features associated with diffuse idiopathic skeletal hyperostosis (DISH)
Authors' conclusion
This is the first characterisation of spatiotemporal features across all phases of DISH, indicating that progression of DISH is characterised by distinct features at different phases along the disease continuum.
Study context
- Population
- Individuals with repeated CT scans of the thoracic spine (83 female, 74 male), followed an average of 2.7 years (range 0.2 to 15.0)83 female and 74 male
- Exposure
- DISH vs Early-phase DISH vs Not meeting either criterion
- Outcome
- Completeness of ectopic bridging across the thoracic spine and corresponding disease status
- Follow-up
- Average of 2.7 years (range from 0.2 to 15.0 years)
Methodological detailsrepeated CT scans of the thoracic spine, Rochester Epidemiology Project
- Repeated CT scans of the thoracic spine
- Rochester Epidemiology Project
Main finding
As reported in the abstract
Spatiotemporal imaging changes along the DISH continuum
Individuals with imaging changes over time resulting in a revised diagnosis along the DISH continuum
Over 15%
Early-phase DISH: new involvement of previously unaffected motion segments, estimated time
2.1 years
Advanced DISH: increased prevalence of complete bridging (average two of three available motion segments), estimated time
2.6-2.9 years
Observational data: associations, not effects.
Original publication
Spatiotemporal changes in imaging features associated with diffuse idiopathic skeletal hyperostosis (DISH). RMD Open. Published 27 April 2024. doi:10. 1136/ rmdopen-2024-004074
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