Silent but significant: subclinical cardiovascular changes in paediatric Behçet's disease
Authors' conclusion
The findings suggest early cardiovascular changes in paediatric BD, including diastolic dysfunction, increased pulmonary arterial pressure, and impaired aortic elasticity.
Study context
- Population
- Paediatric behçet's disease (BD) patients and healthy children without comorbidities or prior cardiovascular diseases
- Participants
- 58 patients
- Exposure
- Paediatric BD vs healthy children
- BDn = 29
- Healthy childrenn = 29reference
Methodological detailscase-control, Mean age of BD patients 15.8 years; disease onset at 12.4 years
- Case-control
- Mean age of BD patients 15.8 years; disease onset at 12.4 years
Main finding
As reported in the abstract
- Elevated LV myocardial performance index (LV MPI) in BD
- Reduced right ventricular systolic function in BD
- Increased pulmonary arterial pressure in BD
- Aortic stiffness significantly higher in BD
- CIMT: no significant differences
- Mild capillary tortuosity in some BD patients
Observational data: associations, not effects.
Original publication
Silent but significant: subclinical cardiovascular changes in paediatric Behçet's disease. Clin Exp Rheumatol. Published 13 April 2025. doi:10.
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