Shoulder Symptom Trajectories Over Four Years: Data From a Longitudinal Study on Osteoarthritis
Authors' conclusion
In this large, four-year study, persistent shoulder symptoms were common and associated with worse clinical outcomes. At least one risk factor for incident symptoms is modifiable.
Study context
- Population
- Osteoarthritis Initiative participants observed annually for four years58% women, mean age 61.2 years
- Participants
- 4,796 participants
- Outcome
- Shoulder symptom (yes/no, side) incidence and prevalence; persistent, incident and intermittent symptoms
- Follow-up
- Four years
Methodological detailslongitudinal, annual observation for four years, latent class growth analysis
- Longitudinal
- Annual observation for four years
- Latent class growth analysis
Main finding
As reported in the abstract
Shoulder symptoms
Baseline shoulder symptom prevalence
22%
Bilateral symptoms among those with baseline symptoms
32%
Persistent symptoms among those reporting right symptoms (260 of 1,886)
14%
Observational data: associations, not effects.
Further findings
Risk factors for persistent symptoms (regression)
- Sleep disturbance, aOR
- 1.97 (95% CI 1.49-2.62)
- Work absenteeism, aOR
- 2.16 (95% CI 1.38-2.62)
- Lower limb weakness, aOR
- 1.76 (95% CI 1.37-2.27)
- Multiple-site joint symptoms (≥3 joints excluding shoulders), aOR
- 4.90 (95% CI 2.79-8.58)
- White race, aOR
- 1.39 (95% CI 1.04-1.88)
Incident and intermittent symptoms
- Lower limb weakness also associated with incident symptoms
- No variables associated with intermittent symptoms
Latent class growth analysis (LCGA) trajectories
- Two trajectories; high-probability-for-symptoms trajectory share of LCGA cohort
- 9%
- High-probability trajectory showed similar relationships to clinical variables as persistent symptoms group
Original publication
Shoulder Symptom Trajectories Over Four Years: Data From a Longitudinal Study on Osteoarthritis. Arthritis Care Res (Hoboken). Published 14 July 2024. doi:10.
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