Should vertebral fracture assessment be performed in Fracture Liaison Service patients with non-vertebral fracture?
Authors' conclusion
Prior hip, humerus, pelvis, forearm, and other fractures are associated with an increased likelihood of previously undiagnosed vertebral fracture, information useful for risk stratification and monitoring.
Study context
- Population
- Patients with T-scores below −1.5 and age 70+ (or younger with height loss or GC use) undergoing bone densitometry with vertebral fracture assessment (VFA) in Manitoba, 2010–2018, without prior clinical vertebral fracture94.4% women
- Participants
- 12,756 patients
- Exposure
- Prior non-vertebral fracture vs no prior fracture
- Outcome
- Vertebral fracture identified on VFA (modified ABQ method)
Methodological detailsregistry-based (Manitoba Bone Density database), multivariable logistic regression
- Registry-based (Manitoba Bone Density database)
- Multivariable logistic regression
Main finding
As reported in the abstract
Vertebral fracture prevalence on VFA
Vertebral fractures identified overall
1925
15.1%
Observational data: associations, not effects.
Original publication
Should vertebral fracture assessment be performed in Fracture Liaison Service patients with non-vertebral fracture? Osteoporos Int. Published 16 November 2022. doi:10. 1007/ s00198-022-06586-6
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