Osteoporosis & bone health

Should vertebral fracture assessment be performed in Fracture Liaison Service patients with non-vertebral fracture?

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Prior hip, humerus, pelvis, forearm, and other fractures are associated with an increased likelihood of previously undiagnosed vertebral fracture, information useful for risk stratification and monitoring.

Study context

Population
Patients with T-scores below −1.5 and age 70+ (or younger with height loss or GC use) undergoing bone densitometry with vertebral fracture assessment (VFA) in Manitoba, 2010–2018, without prior clinical vertebral fracture94.4% women
Participants
12,756 patients
Exposure
Prior non-vertebral fracture vs no prior fracture
Outcome
Vertebral fracture identified on VFA (modified ABQ method)
Methodological detailsregistry-based (Manitoba Bone Density database), multivariable logistic regression
  • Registry-based (Manitoba Bone Density database)
  • Multivariable logistic regression

Main finding

As reported in the abstract

Vertebral fracture prevalence on VFA

Vertebral fractures identified overall

1925

15.1%

Observational data: associations, not effects.

Original publication

Should vertebral fracture assessment be performed in Fracture Liaison Service patients with non-vertebral fracture? Osteoporos Int. Published 16 November 2022. doi:10.1007/s00198-022-06586-6

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