Fibromyalgia & musculoskeletal pain

Sequence Analysis to Phenotype Health Care Patterns in Adults With Musculoskeletal Conditions Using Primary Care Electronic Health Records

Arthritis Care Res (Hoboken)Published Retrospective cohort study

Authors' conclusion

This analysis identified five distinct clusters of health care patterns for patients with MSK conditions in primary care and observed substantial variations in patients' self-reported outcomes and sociodemographic profiles across these different groups of patients.

Study context

Population
Adults (≥18 years) consulting primary care for musculoskeletal (MSK) conditions, Sept 2021–July 2022, North Staffordshire and Stoke-on-Trent, UKavailable for analysis
Participants
1,875 adults
Exposure
Increasing consultation and analgesia vs Low consultation and health care use vs High consultation and health care use vs Low consultation but high analgesia vs Low consultation but moderate health care use
Outcome
Health care pattern clusters (consultations, analgesic prescriptions, imaging, physiotherapy, secondary care referrals) in the 5 years before index consultation, and their association with self-reported outcomes
Methodological detailssequence analysis, primary care electronic health records
  • Sequence analysis
  • Primary care electronic health records

Main finding

As reported in the abstract

Proportion of patients in each health care pattern cluster

Observational data: associations, not effects.

Further findings

Sociodemographic characteristics

High consultation and health care use: predominantly female, older, obesity, more comorbidities, most deprived areas vs low consultation and health care use

Self-reported outcomes

Varied significantly among clusters; worse in high consultation and health care use

Original publication

Sequence Analysis to Phenotype Health Care Patterns in Adults With Musculoskeletal Conditions Using Primary Care Electronic Health Records. Arthritis Care Res (Hoboken). Published 19 April 2025. doi:10.1002/acr.25514

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