Osteoporosis & bone health

Semi-automatic proximal humeral trabecular bone density assessment tool: technique application and clinical validation

Osteoporos IntPublished Diagnostic accuracy study

An erratum to this article was published (Osteoporos Int, Jun 2024 ↗)

Performance · Agreement of proximal humerus BMD, PB-QCT vs PL-QCTResult — go to the resultAverage bias 1.0 mg/cc

Authors' conclusion

Comparison between it and PB-QCT indicated that it could be a reliable shoulder BMD assessment tool with acceptable accuracy and precision.

Study context

Population
Patients with chest CT; proximal humerus trabecular bone density376 shoulders
Participants
188 patients
Comparison
Semi-automatic phantom-less QCT (PL-QCT) vs phantom-based QCT (phantom-based quantitative computed tomography (PB-QCT)) for proximal humerus trabecular BMD on chest CT
Outcome
Accuracy (agreement with PB-QCT) and precision of PL-QCT proximal humerus BMD
Methodological detailsmethod comparison, semi-automatic phantom-less QCT, blinded operators
  • Method comparison
  • Semi-automatic phantom-less QCT
  • Blinded operators

Performance

As reported in the abstract

Agreement of proximal humerus BMD, PB-QCT vs PL-QCT

Average bias

1.0 mg/cc

P > 0.05

Regression analysis between PB-QCT and PL-QCT, R-square
0.9723

Further findings

Short-term repeatability and reproducibility of proximal humerus BMD (CV)

CV repeatability

CV reproducibility

  • Short-term repeatability and reproducibility of proximal humerus BMD (CV): 100 proximal humerus in inter- and intra-operative measurements

Short-term repeatability and reproducibility of proximal humerus BMD (CV)

PB-QCT slightly better than PL-QCT

Original publication

Semi-automatic proximal humeral trabecular bone density assessment tool: technique application and clinical validation. Osteoporos Int. Published 9 March 2024. doi:10.1007/s00198-024-07047-y

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.