The relationship between sarcopenia-related measurements and osteoporosis: The SARCOP study
Authors' conclusion
Loss of muscle mass/function (i.e., sarcopenia) can coexist with loss of trabecular and cortical bone. To this end, grip strength and anterior thigh MT seem to be associated with the lumbar vertebral BMD, while CST is associated with the femoral neck BMD. Lastly, low grip strength might have an association with postmenopausal OP.
Study context
- Population
- Community dwelling postmenopausal women from two physical and rehabilitation medicine outpatient clinics
- Participants
- 546 participants
- Outcome
- Association of sarcopenia-related measurements (US anterior thigh muscle thickness, grip strength, chair stand test, gait speed) with lumbar/femoral BMD and presence of osteoporosis
Methodological detailsconsecutive inclusion, two outpatient clinics
- Consecutive inclusion
- Two outpatient clinics
Main finding
As reported in the abstract
Osteoporosis prevalence
Osteoporosis (T-score ≤ −2.5 SD at L1-L4 and/or femoral neck)
222
40.7%
Low grip strength (< 22 kg) increased risk of osteoporosis (OP) after adjustment for confounders
1.6 times
Observational data: associations, not effects.
Original publication
The relationship between sarcopenia-related measurements and osteoporosis: The SARCOP study. Osteoporos Int. Published 4 October 2022. doi:10. 1007/ s00198-022-06563-z
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