Rheumatoid arthritis

Risk factors associated with venous thromboembolism in rheumatoid arthritis in clinical practice

Clin Exp RheumatolPublished Cross-sectional study

Authors' conclusion

In this study of RA patients, history of VTE and recent hospitalisation were identified as strong risk factors of VTE.

Study context

Population
Consecutive rheumatoid arthritis (RA) patients in clinical practice over a 24-month period, single centre, France (81% women, mean age 59±14 years)15 with venous thromboembolic events (VTE)
Participants
469 patients
Outcome
Classical or disease-related risk factors of VTE occurring after 2018 (JAKi availability in France)
Methodological detailssingle-centre, consecutive patients, multivariate logistic regression
  • Single-centre
  • Consecutive patients
  • Multivariate logistic regression

Main finding

As reported in the abstract

Factors independently associated with VTE (multivariate logistic regression)
Odds ratio (95% CI)
History of previous VTEstrongest risk factor
44.74(8.83–226.68)
Hospitalisation up to 3 months before VTE
6.82(1.60–29.11)
Diabetes
11.23(2.21–57.01)
JAKiamong RA therapies
5.54(1.03–29.72)
VTE after 2018
15 (3%)
Mean interval between VTE and clinical evaluation
4.5±5.6 months

Observational data: associations, not effects.

Original publication

Risk factors associated with venous thromboembolism in rheumatoid arthritis in clinical practice. Clin Exp Rheumatol. Published 26 December 2024. doi:10.55563/clinexprheumatol/7r3hxm

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