Rheumatologic complications of CAR-T Cell therapy. Experience of a single center
Study context
- Population
- Patients treated with CAR-T therapy for haematological malignancies at a single centre, January 2020 to May 2024
- Participants
- 310 patients
- Outcome
- Rheumatic complications after CAR-T therapy
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Rheumatic complications
Patients who developed rheumatic complications (rheumatoid arthritis (RA)-like manifestations with biopsy-proven nodules, palindromic rheumatism, myositis, necrotizing fasciitis, osteonecrosis (ON))
six patients (1.9 %)
Onset after therapy
2 to 11 weeks
RA-like arthritis with subcutaneous nodulosis
2 patients
Observational data: associations, not effects.
Original publication
Rheumatologic complications of CAR-T Cell therapy. Experience of a single center. Semin Arthritis Rheum. Published 27 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →