Rheumatoid cachexia in early rheumatoid arthritis: prevalence and associated variables
Authors' conclusion
RC was highly prevalent in early RA.
Study context
- Population
- Patients with early rheumatoid arthritis (RA); body composition by DXA after a median disease duration of 15 months
- Participants
- 87 patients
- Outcome
- Prevalence of rheumatoid cachexia (fat-free mass index < 10th percentile and fat mass index > 25th percentile)
Methodological detailslogistic regression
- Logistic regression
Main finding
As reported in the abstract
Prevalence of rheumatoid cachexia
Prevalence of rheumatoid cachexia (RC)
24%
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Variables associated with RC (OR per variable)Aerobic capacity | 0.28 (0.09–0.89) | P = 0.030 | |
| Variables associated with RC (OR per variable)Low-intensity physical activity | 0.77 (0.60–0.99) | P = 0.048 | |
| Variables associated with RC (OR per variable)BMI | 0.78 (0.70–0.92) | P = 0.002 | |
| Variables associated with RC (OR per variable)Waist circumference | 0.96 (0.92–0.99) | P = 0.023 | |
| Variables associated with RC (OR per variable)Body weight | 0.94 (0.90–0.98) | P = 0.004 | |
| Variables associated with RC (OR per variable)ESR at diagnosis | 1.02 (1.00–1.05) | P = 0.033 | |
| 0.050.21520Odds ratio (log scale) |
- Variables associated with RC (OR per variable): All associations remained significant after adjusting for age and gender
Original publication
Rheumatoid cachexia in early rheumatoid arthritis: prevalence and associated variables. Scand J Rheumatol. Published 13 October 2021. doi:10.
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