Rheumatoid arthritis-associated interstitial lung disease: clinical characteristics and mortality in a large single-centre cohort
Authors' conclusion
This study underscores the substantial association between serologies, disease activity scores, and smoking history, contributing to the heightened susceptibility to ILD in RA patients.
Study context
- Population
- Patients diagnosed with Rheumatoid Arthritis (RA) according to the 2010 ACR/EULAR classification, April 2015 to April 2021
- Participants
- 153 patients
- Exposure
- RA with interstitial lung disease (ILD) vs RA without ILD
- RA-ILDn = 53
- Without ILDn = 100reference
- Outcome
- Risk factors associated with ILD presence in RA patients
Methodological detailsretrospective chart review, single-centre, multivariable regression
- Retrospective chart review
- Single-centre
- Multivariable regression
Main finding
As reported in the abstract
Factors associated with ILD presence (multivariable analyses)
Smoking status, OR
8.82
Presence of RF, OR
4.98
Elevated DAS28-CRP levels, OR
2.05
Observational data: associations, not effects.
Original publication
Rheumatoid arthritis-associated interstitial lung disease: clinical characteristics and mortality in a large single-centre cohort. Clin Exp Rheumatol. Published 22 May 2024. doi:10. 55563/ clinexprheumatol/ d8m0xv
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