Responsiveness and meaningful thresholds of PROMIS pain interference, fatigue, and physical function forms in adults with idiopathic inflammatory myopathies: Report from the OMERACT Myositis Working Group
Authors' conclusion
This study provides evidence towards the responsiveness of the PROMIS instruments in a large international prospective cohort of adults with IIM supporting their use as PROMs in adult myositis.
Study context
- Population
- Adults with idiopathic inflammatory myositis (IIM) from USA, Netherlands, Korea, Sweden and Australia with two clinical visitscompleted both visits
- Participants
- 114 adults
- Outcome
- Responsiveness and MID of PROMIS pain interference (6a), fatigue (7a) and physical function (8b)
Methodological detailsinternational, multicentre
- International
- Multicentre
Main finding
As reported in the abstract
- Minimal important difference (MID), Pain Interference (points, approximately)
- 2-3
- MID, Fatigue and Physical Function (points, approximately)
- 3-4
- Minimal important change (MIC) for improvement, all instruments (approximately)
- 4-5
- Minimal Detectable Change (MDC), Pain Interference and Physical Function (points)
- 1.7-2
- MDC, Fatigue
- 3.2-3.9
Observational data: associations, not effects.
Original publication
Responsiveness and meaningful thresholds of PROMIS pain interference, fatigue, and physical function forms in adults with idiopathic inflammatory myopathies: Report from the OMERACT Myositis Working Group. Semin Arthritis Rheum. Published 9 December 2023. doi:10.
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