Relationships between diagnostic imaging of first carpometacarpal osteoarthritis and pain, functional status, and disease progression: A systematic review
Authors' conclusion
Imaging findings and radiography-based staging systems generally showed strong associations with pain, but not with functional status or disease progression.
Study context
- Population
- Studies of first CMC osteoarthritis (OA) assessing imaging biomarkers and radiography-based staging46 articles
- Participants
- 28,202 participants
- Outcome
- Association of imaging with pain, functional status and disease progression in first CMC OA
Methodological detailsquality assessed with National Heart, Lung, and Blood Institute tools, PubMed, Embase and Cochrane Library searches plus citation searching; 1969 records screened
- Quality assessed with National Heart, Lung, and Blood Institute tools
- PubMed, Embase and Cochrane Library searches plus citation searching; 1969 records screened
Pooled result
As reported in the abstract
- Osteophytes among the strongest biomarkers for pain across imaging modalities
- Radiographic findings alone: conflicting relationships with pain
- Kellgren-Lawrence staging: consistent associations with pain
- Radiographic, sonographic and MRI findings and staging: little association with functional status
- Same imaging methods: limited ability to predict progression
- Heterogeneity in the study base limited synthesis
Original publication
Relationships between diagnostic imaging of first carpometacarpal osteoarthritis and pain, functional status, and disease progression: A systematic review. Osteoarthritis Cartilage. Published 21 December 2023. doi:10.
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