Relationship Between Number of Different Lower‐Limb Resistance Exercises Prescribed in a Program and Exercise Outcomes in People With Knee Osteoarthritis: A Systematic Review With Meta‐Regression
Authors' conclusion
There was no relationship between the number of different lower-limb resistance exercises prescribed in a program and change in knee pain or self-reported function.
Study context
- Population
- People with knee OA in RCTs of land-based resistance exercise vs nonexercise interventions; CENTRAL, MEDLINE and Embase searched up to January 4, 2024
- Participants
- 3,364 people44 trials
- Comparison
- Number of different lower-limb resistance exercises prescribed
- Outcome
- Relationship between number of different exercises prescribed and standardized mean differences (SMDs) for pain and function
Methodological detailscovariates: intervention duration, frequency per week, resistance exercise machine use, comparator type
- Covariates: intervention duration, frequency per week, resistance exercise machine use, comparator type
Pooled result
As reported in the abstract
Relationship between number of prescribed exercises and change in pain and self-reported function (meta-regression)
Change in pain: slope coefficient, SMD units (95% CI −0.14 to 0.05); no relationship
−0.04
Self-reported function: SMD (95% CI −0.12 to 0.05); no relationship
−0.04
Number of resistance exercises, range (mean ± SD 5.0 ± 3.0)
1 to 12
Further pooled results
Sensitivity analysis after removing 31 trials with overall unclear/high risk of bias
- No change in relationships
Original publication
Relationship Between Number of Different Lower‐Limb Resistance Exercises Prescribed in a Program and Exercise Outcomes in People With Knee Osteoarthritis: A Systematic Review With Meta‐Regression. Arthritis Care Res (Hoboken). Published 14 January 2025. doi:10. 1002/ acr. 25476
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