Lupus & antiphospholipid syndrome

Real world application of the 2023 ACR/EULAR antiphospholipid antibody syndrome classification criteria in a pharmacist directed anticoagulation clinic

LupusPublished Retrospective chart review

Authors' conclusion

Results from this study indicate that APS continues to be a complex disease state with challenges in diagnosis and classification.

Study context

Population
Patients previously diagnosed with APS on anticoagulation managed by ambulatory care clinical pharmacists, single centrepreviously diagnosed APS
Participants
51 participants
Outcome
Number of patients meeting 2023 ACR/EULAR APS classification criteria
Methodological detailssingle-centre, descriptive statistics
  • Single-centre
  • Descriptive statistics

Main finding

As reported in the abstract

Classification by 2023 ACR/EULAR APS criteria

Met classification criteria

12

23.5%

Did not meet classification criteria

33

64.7%

Insufficient data

6

11.7%

Observational data: associations, not effects.

Further findings

Reasons for not meeting criteria

Did not meet laboratory criteria
13 (39.4%)
Did not meet clinical criteria
6 (18.2%)
Did not meet both laboratory and clinical criteria
14 (42.4%)
  • Denominator printed as 27 patients that did not meet criteria

Antibody positivity among the 12 meeting criteria

Triple positive
2 (16.7%)
Double positive
3 (25%)
Single positive
7 (58.3%)

Anticoagulation type

Warfarin
42 (82.3%)
Direct oral anticoagulants
4 (19%)
Low molecular weight heparin
3 (5.8%)
Fondaparinux
2 (3.9%)

Original publication

Real world application of the 2023 ACR/EULAR antiphospholipid antibody syndrome classification criteria in a pharmacist directed anticoagulation clinic. Lupus. Published 14 November 2024. doi:10.1177/09612033241301173

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