Racial Differences in Multimorbidity and Comorbidities in Rheumatoid Arthritis
Main finding · Multimorbidity ≥2 comorbiditiesResult — go to the resultAdjusted odds 2.19 95% CI 2.16–2.23Authors' conclusion
Multimorbidity is a problem for all RA patients.
Study context
- Population
- Enrollees in OptumLabs Data Warehouse, 2010 to 2019 (mean age 59.6, 76% female)mean age 59.6, 76% female
- Participants
- 154,391 vs 154,391
- Comparison
- Rheumatoid arthritis (RA) cases vs matched non-RA controls, within each race and ethnicity
- RA casesn = 154,391
- Controlsn = 154,391reference
- Outcome
- Multimorbidity (≥2 or ≥5 validated comorbidities), within each race and ethnicity
Methodological detailsmatched 1:1 on age, sex, race and ethnicity, region, index date of RA, and insurance coverage duration, logistic regression
- Matched 1:1 on age, sex, race and ethnicity, region, index date of RA, and insurance coverage duration
- Logistic regression
Main finding
Multimorbidity ≥2 comorbidities
Adjusted odds
2.19
95% CI 2.16–2.23
As reported in the abstract
Observational data: associations, not effects.
Further findings
Renal disease in White enrollees
P < 0.001
| Outcome | Adjusted odds (95% CI) |
|---|---|
| Multimorbidity ≥5 comorbidities | 2.06 (2.02–2.09) |
- Valvular heart disease in Black and White enrollees
- P < 0.001
- Valvular heart disease in Black and White enrollees — Black: RA cases vs controls
- 3.2% versus 2.6%
- Valvular heart disease in Black and White enrollees — White: RA cases vs controls
- 2.8% versus 2.2%
Multimorbidity ≥2/≥5 by race and ethnicity
- Black enrollees (most), ≥2/≥5
- 73.1%, 34.3%
- Asian enrollees (least), ≥2/≥5
- 52.4%, 17.3%
Original publication
Racial Differences in Multimorbidity and Comorbidities in Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 31 October 2022. doi:10. 1002/ acr. 25020
Composed by AI from the published abstract and checked against it. How Briefs are made →