Across rheumatic diseases

Racial and Ethnic Distribution of Rheumatic Diseases in Health Systems of the National Patient-Centered Clinical Research Network

J RheumatolPublished Cross-sectional study

Authors' conclusion

These data provide important information on the prevalence of RMDs by race and ethnicity in the United States.

Study context

Population
Adults with ≥ 2 diagnosis codes for rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), osteoporosis, granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinophilic granulomatosis with polyangiitis (EGPA), giant cell arteritis (GCA) or TAK in PCORnet EHRs, 2013–2018
Participants
28,059,546 adults
Exposure
Prevalence of 8 rheumatic and musculoskeletal diseases (RMDs) across racial and ethnic groups
Outcome
Relative prevalence of 8 RMDs across racial and ethnic groups
Methodological detailselectronic health records, multicentre (PCORnet institutions and systems)
  • Electronic health records
  • Multicentre (PCORnet institutions and systems)

Main finding

As reported in the abstract

Prevalence of RMDs by race and ethnicity
  • Osteoporosis (OP), RA and the vasculitides all more common in White vs Black or African American

Observational data: associations, not effects.

Further findings

OutcomeValuesOR (95% CI)
RA prevalence (/1000)American Indian or Alaska Nativevs WhiteAmerican Indian or Alaska Native 11.57 /1000 · White 10.11 /10001.15 (1.09–1.22)
SLE prevalence (/1000) by raceBlack or African Americanvs WhiteBlack or African American 6.73 /1000 · American Indian or Alaska Native 3.82 /1000 · Asian 3.39 /1000 · White 2.80 /10002.43 (2.39–2.46)
SLE prevalence (/1000) by raceAmerican Indian or Alaska Nativevs White1.39 (1.25–1.53)
SLE prevalence (/1000) by raceAsianvs White1.26 (1.21–1.31)
SLE prevalence (/1000) by ethnicityHispanicvs Non-HispanicHispanic 3.93 /1000 · Non-Hispanic 3.45 /10001.14 (1.12–1.16)
TAK prevalence (/1000)Asianvs WhiteAsian 0.05 /1000 · White 0.04 /10001.43 (1.00–2.03)

Original publication

Racial and Ethnic Distribution of Rheumatic Diseases in Health Systems of the National Patient-Centered Clinical Research Network. J Rheumatol. Published 1 September 2023. doi:10.3899/jrheum.2022-1300

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