Quantifying Cutaneous Dermatomyositis: A Novel 3D Image–Based Approach
Authors' conclusion
Our results demonstrate favorable validity and responsiveness of the 3D images for evaluating rashes in patients with DM. The 3D image-derived rash area and redness are significant predictors of CDASI scores.
Study context
- Population
- Patients with dermatomyositis (DM) (81.5% female, 96.3% White; median age 50.0 years)
- Participants
- 27 patients
- Comparison
- 3D image disease activity score vs CDASI and patient-reported outcome measures (PROMs)
- Outcome
- Feasibility of 3D image-based assessment of cutaneous DM activity: construct validity and responsiveness of 3DAS vs CDASI and PROMs (Spearman r)
Methodological details2 timepoints
- 2 timepoints
Performance
As reported in the abstract
Construct validity: correlation of 3DAS with CDASI
Spearman r, 3DAS vs CDASI (strong correlation); also correlated strongly with PROMs
r = 0.83
P < 0.001
Further findings
Responsiveness: absolute change from baseline in 3DAS vs CDASI
- Spearman r (strong correlation)
- r = 0.61; P = 0.004
Generalized linear regression: 3D rash area and redness as predictors of CDASI
- Rash area and redness from 3D images were significant predictors of CDASI score
Baseline CDASI score
- Median (IQR) CDASI
- 6.0 (IQR 0.0-17.0)
Original publication
Quantifying Cutaneous Dermatomyositis: A Novel 3D Image–Based Approach. J Rheumatol. Published 1 October 2025. doi:10.
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