Lupus & antiphospholipid syndrome
Psychological impact of life events in systemic lupus erythematosus patients – Differences between flares and remission
Authors' conclusion
There is a high prevalence of pathological levels of stress among SLE patients. SLE patients with recent flares report less psychological impact from life events, both positive and negative, independent of other psychological or pharmacological factors.
Study context
- Population
- Adult female Systemic lupus erythematosus (SLE) patientsall female
- Participants
- 47 patients
- Exposure
- SLE patients with recent flares vs without recent flares
- Recent flaren = 10
- Outcome
- Life events (Life Experience Survey (LES)), previous year
Main finding
As reported in the abstract
- Recent flare: fewer life events, with lower positive, negative and total weightings sums vs no flare
Observational data: associations, not effects.
Further findings
Psychometric measures (Perceived Stress Scale (PSS-10), Hospital Anxiety and Depression Scale (HADS)), whole cohort
- Pathological levels of stress in the previous month
- 42.2%
- Anxiety symptoms
- 48.9%
- High risk for an anxiety disorder
- 34%
- Did not differ significantly between recent flare and no-flare groups
Original publication
Psychological impact of life events in systemic lupus erythematosus patients – Differences between flares and remission. Lupus. Published 21 July 2024. doi:10.
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