Psychiatric Morbidity Is Common Among Children With Juvenile Idiopathic Arthritis: A National Matched Cohort Study
Main finding · Psychiatric diagnosisResult — go to the resultAdjusted hazard ratio 1.17 95% CI 1.02–1.34Authors' conclusion
Children with JIA had a higher risk of psychiatric diagnoses compared to their peers, especially diagnoses of depression and adjustment disorders. The association between JIA and psychiatric disease did not depend on parental SES.
Study context
- Population
- Children born 1995–2014 in Denmark, with juvenile idiopathic arthritis (JIA) (mean age at diagnosis 8.1 years) and matched peersmatched cohort
- Exposure
- Children with JIA vs age- and sex-matched reference children
- JIAn = 2,086
- Outcome
- Psychiatric diagnosis
Methodological detailsnational registers, 100 age- and sex-matched children per index child, Cox proportional hazard model
- National registers
- 100 age- and sex-matched children per index child
- Cox proportional hazard model
Main finding
As reported in the abstract
Adjusted hazard ratio
1.17
95% CI 1.02–1.34
JIAvs Reference
aHR 1.17 (95% CI 1.02–1.34)
Observational data: associations, not effects.
Further findings
Specific psychiatric diagnoses
- Relevant associations found only for depression and adjustment disorders
Effect modification by parental socioeconomic status (SES)
- No modifying effect of SES
Original publication
Psychiatric Morbidity Is Common Among Children With Juvenile Idiopathic Arthritis: A National Matched Cohort Study. J Rheumatol. Published 15 June 2023. doi:10. 3899/ jrheum. 2023-0084
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