Pediatric rheumatology

Psychiatric Morbidity Is Common Among Children With Juvenile Idiopathic Arthritis: A National Matched Cohort Study

J RheumatolPublished Matched cohort study

Main finding · Psychiatric diagnosisResult — go to the resultAdjusted hazard ratio 1.17 95% CI 1.02–1.34

Authors' conclusion

Children with JIA had a higher risk of psychiatric diagnoses compared to their peers, especially diagnoses of depression and adjustment disorders. The association between JIA and psychiatric disease did not depend on parental SES.

Study context

Population
Children born 1995–2014 in Denmark, with juvenile idiopathic arthritis (JIA) (mean age at diagnosis 8.1 years) and matched peersmatched cohort
Exposure
Children with JIA vs age- and sex-matched reference children
  • JIAn = 2,086
Outcome
Psychiatric diagnosis
Methodological detailsnational registers, 100 age- and sex-matched children per index child, Cox proportional hazard model
  • National registers
  • 100 age- and sex-matched children per index child
  • Cox proportional hazard model

Main finding

As reported in the abstract

Adjusted hazard ratio

1.17

95% CI 1.02–1.34

JIAvs Reference
aHR 1.17 (95% CI 1.02–1.34)

Observational data: associations, not effects.

Further findings

Specific psychiatric diagnoses

Relevant associations found only for depression and adjustment disorders

Effect modification by parental socioeconomic status (SES)

No modifying effect of SES

Original publication

Psychiatric Morbidity Is Common Among Children With Juvenile Idiopathic Arthritis: A National Matched Cohort Study. J Rheumatol. Published 15 June 2023. doi:10.3899/jrheum.2023-0084

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