Pediatric rheumatology

Prevalence of ultrasound and clinical findings suggestive of inflammatory arthritis in children with skin psoriasis

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

US abnormalities were higher in the Sy group, with synovitis and enthesitis as the most prevalent findings.

Study context

Population
Consecutive children with skin psoriasis (PsO)26 girls (46%)
Participants
57 children
Exposure
Symptomatic vs asymptomatic children with PsO
  • Asymptomatic (Asy)n = 42reference
  • Symptomatic (Sy)n = 15
Outcome
Prevalence of clinical and US (grey-scale and Doppler) abnormalities in joints, periarticular structures and nails
Methodological detailsconsecutive children, independent examiners blinded to each other's assessment
  • Consecutive children
  • Independent examiners blinded to each other's assessment

Main finding

As reported in the abstract

Presence of US abnormalities

Observational data: associations, not effects.

Further findings

US synovitis

US enthesitis

Systemic treatment

P < 0.01

OutcomeAsySyP value
Age9 (SD 3) years— withheld: not confirmed against the abstractP < 0.05
Tender joint count (children with tender joints)0 events— not stated in the abstractP < 0.001
Swollen joint count (children with swollen joints)0 events20%P < 0.01
Entheseal pain0 events66.7%P < 0.001
Classified with juvenile PsA (JPsA)— not stated in the abstract3 events

— not stated in the abstract

— withheld: the automatic checks could not confirm the value against the abstract

PsO duration
P < 0.001

US synovitis

Statistically significant difference between Asy and Sy

US enthesitis

Statistically significant difference between Asy and Sy

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Prevalence of ultrasound and clinical findings suggestive of inflammatory arthritis in children with skin psoriasis. Rheumatology (Oxford). Published 4 August 2023. doi:10.1093/rheumatology/kead398

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