Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) and early-phase DISH across the lifespan of an American population

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

The continuum of imaging features associated with DISH is detected in more than one in four adults and both sexes in an American population.

Study context

Population
Individuals over 19 years of age with CT of the thoracic spine from a Northern US catchment area16,710 motion segments
Participants
1,536 unique images
Exposure
Female vs Male
  • Femalen = 766
  • Malen = 770
Outcome
Prevalence of DISH and early-phase DISH
Methodological detailsretrospective image evaluation, stratified random sampling by age and sex, Rochester Epidemiology Project
  • Retrospective image evaluation
  • Stratified random sampling by age and sex
  • Rochester Epidemiology Project

Main finding

As reported in the abstract

Early-phase DISH prevalence, overall
13.2%
Early-phase DISH prevalence, female
10.4%
Early-phase DISH prevalence, male
15.8%
Established DISH prevalence, overall
14.2%
Established DISH prevalence, female
7.4%
Established DISH prevalence, male
20.9%

Observational data: associations, not effects.

Further findings

Motion segments with ectopic mineralization in the thoracic spine

Proportion of all motion segments evaluated
40.5%

Heterogeneity within each disease classification

Remarkable heterogeneity by extent of thoracic spine affected and degree of mineralization

Original publication

Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) and early-phase DISH across the lifespan of an American population. Rheumatology (Oxford). Published 22 July 2023. doi:10.1093/rheumatology/kead362

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