Prevalence of Comorbidities and Poor Prognostic Factors Among Patients With Rheumatoid Arthritis in Bangladesh
Authors' conclusion
The prevalence of multimorbidity is high among patients with RA in Bangladesh, particularly early cardiovascular disease risk.
Study context
- Population
- Patients with rheumatoid arthritis (RA) at 2 tertiary care hospitals in Bangladesh
- Participants
- 653 patients
- Outcome
- Prevalence of comorbidities
Methodological details2 tertiary care hospitals, logistic regression
- 2 tertiary care hospitals
- Logistic regression
Main finding
As reported in the abstract
≥ 1 comorbidity (prevalence)
- Patients with ≥ 1 comorbidity
- 646 (98.9%)
- Dyslipidemia
- 75.8%
- Obesity
- 58.7%
- Hypertension
- 42.7%
- Type 2 diabetes mellitus
- 30.3%
- Osteoporosis (OP)
- 15.6%
Observational data: associations, not effects.
Further findings
Mean
| Outcome | Older (≥ 45 years) | Younger | P value |
|---|---|---|---|
| CCI survival index, older (≥ 45 years) vs younger patientsSignificantly lower in older patients | 68.7 (SD 26.7) | 93.3 (SD 6.7) | P < 0.001 |
Factors associated with comorbidities: age ≥ 45 years
- Coronary artery disease, OR
- 9.71 (1.91-178.00) (95% CI)
- OP, OR
- 19.60 (5.96-121.00) (95% CI)
- Infectious diseases, OR
- 1.60 (1.03-2.54) (95% CI)
- Independently associated
Factors associated with comorbidities: female sex
- Cardiovascular risk (lower), OR
- 0.27 (0.11-0.62) (95% CI)
- OP, OR
- 3.55 (1.71-8.37) (95% CI)
- Gastrointestinal (GI) disorders, OR
- 2.18 (1.37-3.56) (95% CI)
Infection risk with tsDMARD and bDMARD use
- tsDMARD, OR
- 14.80
- bDMARD, OR
- 4.11
GI comorbidities
- High DAS28-CRP and ESR values linked to GI comorbidities
Original publication
Prevalence of Comorbidities and Poor Prognostic Factors Among Patients With Rheumatoid Arthritis in Bangladesh. J Rheumatol. Published 15 April 2026. doi:10.
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