Lupus & antiphospholipid syndrome

Prevalence of coeliac disease in patients with systemic lupus erythematosus: a systematic review and meta-analysis

Lupus Sci MedPublished Systematic review and meta-analysis

Authors' conclusion

In this meta-analysis, we found a weighted pooled prevalence of biopsy-verified CD in patients with SLE comparable with the prevalence in the general population.

Study context

Population
Patients with SLE; Medline, Embase, Cochrane and Web of Science Core Collection, 1 January 1990 to 9 July 202314 studies
Outcome
Pooled prevalence of biopsy-verified coeliac disease (CD)
Methodological detailsmeta-regression, Joanna Briggs Institute Critical Appraisal Tool
  • Meta-regression
  • Joanna Briggs Institute Critical Appraisal Tool

Pooled result

As reported in the abstract

Biopsy-verified CD, weighted pooled prevalence

SLE

0.7%

14 events

Further pooled results

OutcomeValues
CD serological markers, weighted pooled prevalenceSLE 3.7% (95% CI 1.4–6.7)
  • Coeliac disease (CD) serological markers, weighted pooled prevalence: 1063 patients with SLE

Meta-regression of CD prevalence

No associations between CD prevalence and study characteristics, demographics and quality assessment scores

Original publication

Prevalence of coeliac disease in patients with systemic lupus erythematosus: a systematic review and meta-analysis. Lupus Sci Med. Published 13 February 2024. doi:10.1136/lupus-2023-001106

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