Lupus & antiphospholipid syndrome
Prevalence and predictive factors associated with sustained remission in SLE: a systematic review
Authors' conclusion
Long-term remission is an achievable state in SLE with current treatment. Studies report a striking heterogeneity in the current prevalences.
Study context
- Population
- Adult patients with SLE (Embase and Medline via Ovid)20 studies
- Outcome
- Prevalence of sustained remission (≥2 years) in SLE and its predictive factors
- Follow-up
- 2 years or more
Methodological detailsDefinition of remission differed between studies
- Definition of remission differed between studies
Pooled result
As reported in the abstract
Prevalence of long-term remission
Prevalence ranged across studies, depending on remission definition
0.3% to 63%
Further pooled results
Predictive factors of sustained remission
- Older age at diagnosis, lower disease activity at baseline and absence of renal involvement were the most commonly found factors likely associated with sustained remission
Original publication
Prevalence and predictive factors associated with sustained remission in SLE: a systematic review. Lupus Sci Med. Published 28 November 2025. doi:10.
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