Lupus & antiphospholipid syndrome
Pregnancy Outcomes in a Diverse US Lupus Cohort
Authors' conclusion
We found that approximately 74% of pregnancies in patients with SLE ended in live birth, with modest variability in spontaneous abortion by race and ethnicity, nephritis history, and aPL status.
Study context
- Population
- Pregnancies with outcomes observed 2011–2020 among patients with prevalent systemic lupus erythematosus (SLE), Kaiser Permanente Northern California; racially and ethnically diverse cohort
- Participants
- 453 participants657 pregnancies
- Outcome
- Live birth rate
Methodological detailselectronic health records
- Electronic health records
Main finding
As reported in the abstract
Pregnancy outcomes
Live birth
74%
Spontaneous abortion
23%
Ectopic or molar pregnancy
2%
Stillbirth
<1%
Observational data: associations, not effects.
Further findings
- Live births by race and ethnic group
- 72%-79%
- Live births by aPL status
- 69.5%-77%
- Live births by nephritis history
- 71%-75%
- Limited variability
Original publication
Pregnancy Outcomes in a Diverse US Lupus Cohort. Arthritis Care Res (Hoboken). Published 6 February 2024. doi:10.
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