Fibromyalgia & musculoskeletal pain
Predictors of Pain Reduction Among Fibromyalgia Patients Using Medical Cannabis: A Long‐Term Prospective Cohort Study
Authors' conclusion
Our findings provide preliminary insight into the potential mechanisms of action underlying pain reductions among patients with FM who are using medical cannabis.
Study context
- Population
- Patients with fibromyalgia (FM) initiating medical cannabis under the care of physicians
- Participants
- 323 patients
- Outcome
- Whether changes in pain intensity after initiation of medical cannabis could be attributed to concurrent reductions in negative affect and sleep problems
- Follow-up
- 12 months
Methodological details12-month follow-up, multilevel mediation analyses, Attrition rate 75% at 12 months
- 12-month follow-up
- Multilevel mediation analyses
- Attrition rate 75% at 12 months
Main finding
As reported in the abstract
Mediation of pain intensity reduction
- Reductions in pain intensity partly explained by concurrent reductions in sleep problems
- P < 0.001
- Reductions in pain intensity partly explained by concurrent reductions in negative affect
- P < 0.001
Observational data: associations, not effects.
Original publication
Predictors of Pain Reduction Among Fibromyalgia Patients Using Medical Cannabis: A Long‐Term Prospective Cohort Study. Arthritis Care Res (Hoboken). Published 3 February 2023. doi:10.
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